Scientific Publications
Scientific Publications
Fröba et al., Int. J. Mol. Sci. 2021, 22, 13202. https://doi.org/ 10.3390/ijms222413202
Iota-Carrageenan Inhibits Replication of SARS-CoV-2 and the Respective Variants of Concern Alpha, Beta, Gamma and Delta
Scientific Publications
Morokutti-Kurz M et al., Int J Gen Med. 2021;14:5241-5249 https://doi.org/10.2147/IJGM.S325861
The Saliva of Probands Sucking an Iota-Carrageenan Containing Lozenge Inhibits Viral Binding and Replication of the Most Predominant Common Cold Viruses and SARS-CoV-2
Scientific Publications
Morokutti-Kurz et al., PLoS ONE, 2021, 16(2): e0237480.
Iota-carrageenan neutralizes SARS-CoV-2 and inhibits viral replication in vitro
Scientific Publications
Nakowitsch et al., Pharmaceutics 2020, 12(9), 847
Saponin Micelles Lead to High Mucosal Permeation and In Vivo Efficacy of Solubilized Budesonide
Scientific Publications
Morokutti-Kurz et al., bioRxiv. 2020; 10.1101/2020.07.28.224733
SARS-CoV-2 in-vitro neutralization assay reveals inhibition of virus entry by iota-carrageenan
Scientific Publications
Zieglmayer et al., Clin Exp Allergy. 2020; 00:1–13.
Fast effectiveness of a solubilized low‐dose budesonide nasal spray in allergic rhinitis
Scientific Publications
Zhang et al., Invest Ophthalmol Vis Sci. 2020; 61(1):4.
Topical Pergolide Enhance Corneal Nerve Regrowth Following Induced Corneal Abrasion
Scientific Publications
Siegl et al., European Journal of Pharmaceutics and Biopharmaceutics 134, 2019, 88-95
Pharmacokinetics of topically applied tacrolimus dissolved in Marinosolv, a novel aqueous eye drop formulation
Scientific Publications
Graf et al., International Journal of General Medicine 2018, 11:275–28
Development of a nasal spray containing xylometazoline hydrochloride and iota- carrageenan for the symptomatic relief of nasal congestion caused by rhinitis and sinusitis
Scientific Publications
Morokutti-Kurz et al., International Journal of General Medicine 2017, 10:53–60
Amylmetacresol/2,4-dichlorobenzyl alcohol, hexylresorcinol, or carrageenan lozenges as active treatments for sore throat
Scientific Publications
Morokutti-Kurz et al., PLOS one 2015, 10:6
The Intranasal Application of Zanamivir and Carrageenan Is Synergistically Active against Influenza A Virus in the Murine Model
Scientific Publications
Hebar et al., PLOS one 2015, 10:4
Non-Clinical Safety Evaluation of Intranasal Iota-Carrageenan
Scientific Publications
Koenighofer et al., Multidisciplinary Respiratory Medicine 2014, 9:57
Carrageenan nasal spray in virus confirmed common cold: individual patient data analysis of two randomized controlled trials
Scientific Publications
Ludwig et al., Respiratory Research 2013, 14:124
Efficacy of a Carrageenan nasal spray in patients with common cold: a randomized controlled trial
Scientific Publications
Fazekas et al., BMC Complementary and Alternative Medicine 2012, 12:147
Lessons learned from a double-blind randomised placebo-controlled study with a iota-carrageenan nasal spray as medical device in children with acute symptoms of common cold
Scientific Publications
Leibbrandt et al., PLOS one 2010, 5:12
Iota-Carrageenan Is a Potent Inhibitor of Influenza A Virus Infection
Scientific Publications
Eccles et al., Respiratory Research 2010, 11:108
Efficacy and safety of an antiviral Iota-Carrageenan nasal spray: a randomized, double-blind, placebo-controlled exploratory study in volunteers with early symptoms of the common cold
Scientific Publications
Grassauer et al., Virology Journal 2008, 5:107
Iota-Carrageenan is a potent inhibitor of rhinovirus infection
Related Publications
Bovard et al., Biochemistry and Biophysics Reports, Volume 29, 2022, 101187, https://doi.org/10.1016/j.bbrep.2021.101187
Iota-carrageenan extracted from red algae is a potent inhibitor of SARS‐CoV-2 infection in reconstituted human airway epithelia
Related Publications
Ratcliffe et al., PLoS Pathog 2021; 17(11): e1010079. https://doi.org/10.1371/journal.ppat.1010079
Nasal therapy — The missing link in optimising strategies to improve prevention and treatment of COVID-19
Related Publications
Bansal et al., PLoS ONE 2021; 16(11): e0259943. https://doi.org/10.1371/journal.pone.0259943
Iota-carrageenan and xylitol inhibit SARS-CoV-2 in Vero cell culture
Related Publications
Chahla et al., medRxiv 2021; 03.26.21254398; doi: https://doi.org/10.1101/2021.03.26.21254398
A randomized trial - intensive treatment based in Ivermectin and Iota-Carrageenan as pre-exposure prophylaxis for Covid-19 in healthcare agents
Related Publications
Amtha et al., Teikyo Medical Journal; 2021, 44 (05), 1659-1669
PVP-I and Iota-Carrageenan Improve Subjective Clinical Symptoms In COVID-19 Emergency Hospital Wisma Atlet, Indonesia: A Single-Blind Randomized Clinical Trial.
Related Publications
Figueroa et al., Int J Gen Med. 2021;14:6277-6286 https://doi.org/10.2147/IJGM.S328486
Efficacy of a Nasal Spray Containing Iota-Carrageenan in the Postexposure Prophylaxis of COVID-19 in Hospital Personnel Dedicated to Patients Care with COVID-19 Disease
Related Publications
Auth, J. et al., Int. J. Mol. Sci. 2021, 22, 10205. https://doi.org/ 10.3390/ijms221910205
Lectin from Triticum vulgaris (WGA) Inhibits Infection with SARS-CoV-2 and Its Variants of Concern Alpha and Beta
Related Publications
Umar et al., Journal of polymers and the environment, 1-20. 9 Sep. 2021, doi:10.1007/s10924-021-02272-6
Polymeric Materials as Potential Inhibitors Against SARS-CoV-2
Related Publications
Alsaidi et al., Mar. Drugs 2021, 19, 418. https://doi.org/10.3390/md19080418
Griffithsin and Carrageenan Combination Results in Antiviral Synergy against SARS-CoV-1 and 2 in a Pseudoviral Model
Related Publications
M. Suchomel et. al; Austrian Society for Hygiene, Microbiology and Preventive Medicine
Use of gargle solutions and nasal sprays - two other allies in the defense against viral colds even in times of Covid-19 (German Only)
Related Publications
Hemilä et al., Pharmacology Research & Perspectives 2021; DOI: 10.1002/prp2.810
Carrageenan nasal spray may double the rate of recovery from coronavirus and influenza virus infections: Re-analysis of randomized trial data
Related Publications
Hoseini-Tavassol et al., Infectious Disorders - Drug Targets, 2021, 20, 1-7
Natural Derived Nasal Spray; A Proposed Approach for COVID-19 Disease Control
Related Publications
Bichiri et al., Med Pharm Rep. 2021 Jan; 94(1): 28–34.
Safety and efficacy of iota-carrageenan nasal spray in treatment and prevention of the common cold
Related Publications
Schütz et al., American Journal of Physiology-Lung Cellular and Molecular Physiology, 2021, https://doi.org/10.1152/ajplung.00552.2020
Carrageenan containing over-the-counter nasal and oral sprays inhibit SARS-CoV-2 infection of airway epithelial cultures
Related Publications
Kramer et al., GMS Hygiene and Infection Control 2021, Vol. 16, ISSN 2196-5226
Virucidal gargling and virucidal nasal spray
Related Publications
Hirsch et al., Journal of Infectious Diseases & Travel Medicine 2020, 4 (S1): 000S1-007
Covid 19 and Ivermectin Prevention and Treatment Update
Related Publications
Carvallo et al., Journal of Biomedical Research and Clinical Investigation 2020; Volume 2 Isue 1.1007
Study of the Efficacy and Safety of Topical Ivermectin + Iota-Carrageenan in the Prophylaxis against COVID-19 in Health Personnel
Related Publications
Clausen et al., Cell 2020, 2020.09.033
SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2
Related Publications
Lee, Marine Drugs 2020, 18, 435
Carrageenans as Broad-Spectrum Microbicides: Current Status and Challenges
Related Publications
Bansal et al., bioRxiv. 2020; 10.1101/2020.08.19.225854
Iota-carrageenan and Xylitol inhibit SARS-CoV-2 in cell culture
Related Publications
Chen et al., International Journal of Biological Macromolecules, 2020, 164, 331-343
Application prospect of polysaccharides in the development of anti-novelcoronavirus drugs and vaccines
Related Publications
Pereira, L., Critchley, A.T., Journal of Applied Phycology 2020
The COVID 19 novel coronavirus pandemic 2020: seaweeds to the rescue? Why does substantial, supporting research about the antiviral properties of seaweed polysaccharides seem to go unrecognized by the pharmaceutical community in these desperate times?
Related Publications
Eccles, The Open Virology Journal 2020, 14:9
Iota-Carrageenan as an Antiviral Treatment for the Common Cold
Related Publications
Eccles et al., Respiratory Research 2015, 16:121
Efficacy and safety of iota-carrageenan nasal spray versus placebo in early treatment of the common cold in adults: the ICICC trial
Scientific Posters
Zieglmayer et al. 2020
A novel nasal spray formulation of solubilized budesonide (Budesolv 10) promptly improves asthmatic symptoms in patients suffering from grass pollen allergic symptoms induced in an allergen exposure chamber
Scientific Posters
Zieglmayer et al. 2019
Rapid Onset Of Action Of A Novel Budesonide Nasal Spray In Grass Pollen Allergic Rhinitis
Scientific Posters
Siegl et al. 2019
Tacrosolv: A novel aqueous tacrolimus eye drop formulation for the treatment of immune mediated eye diseases
Scientific Posters
Nakowitsch et al. 2016
A solubilized aqueous budesonide formulation showed higher anti-inflammatory therapeutic efficacy in a murine pulmonary inflammation model compared to marketed products
Scientific Posters
Nakowitsch et al. 2016
Increased uptake of lipophilic immunosuppressive compounds in cornea and retina based on solubilization in an aqueous formulation
Scientific Posters
Ludwig et al. 2013
Carrageenan nasal spray against common cold: a pooled analysis of two randomized, double-blind, placebo controlled studies
Scientific Posters
Morokutti-Kurz et al. 2013
Combinational antiviral therapy with Carragelose® and Zanamivir is synergistically active against influenza A virus infection
Scientific Posters
Nakowitsch et al. 2013
Combination of a corticosteroid and an anti-viral intranasal therapy
Scientific Posters
Nakowitsch et al. 2012
Antiviral Polymers - A Novel Concept for Prophylactic and Therapeutic Interventions
Scientific Posters
Reutterer et al. 2011
Combination of carrageenan and a neuraminidase inhibitor as superior treatment for influenza A
Scientific Posters
Eccles et al. 2010
Efficacy and safety of an antiviral Iota-Carrageenan nasal spray: a randomized, double-blind, placebo-controlled Pilot study in volunteers with early symptoms of the common cold
Scientific Posters
Grassauer et al. 2009
Iota-Carrageenan is a potent Inhibitor of rhinovirus infection